Glucagon-like peptide 1 (GLP-1) agonists are a class of drugs that can help treat obesity by inducing weight loss:
How they work
GLP-1 agonists mimic the body's natural production of GLP-1, which helps regulate insulin production and food intake. GLP-1 agonists can make people feel full and slow down digestion.
Effectiveness
In trials, GLP-1 agonists have produced weight loss of 12–18% that's greater than other pharmacologic therapies. For example, semaglutide 2.4 mg once weekly can result in a mean weight loss of 15–17%.